Yvette joined Memorial Sloan Kettering in 2001 as a registered nurse on the pediatric inpatient unit where she cared for children undergoing bone marrow transplantation, chemotherapy, and various other cancer-related procedures.
She became a nurse practitioner in 2008, and in 2010 transferred into a position as a nurse practitioner at Memorial Sloan to the inpatient Adult Bone Marrow Transplant Service. She works collaboratively with  physicians to manage the care of people undergoing autologous and allogeneic transplants, as well as people who are readmitted for post-transplant complications such as infections and severe graft-versus-host disease.

In 2021 she joined Newark Beth Israel, RWJBH Frederick B. Cohen, M.D. Comprehensive Cancer and Blood Disorders Center and worked with both Oncology and hematology adult patients including leukemia, lymphoma, breast, lung, hemophilia and sickle cell patients.

In June 2022 she became the lead Nurse Practitioner for the sickle cell population with adults and transitioned from pediatric patients to adult clinic. She is currently working on her Hematology Advance Practitioner Certification. Yvette is also an active member of the National Alliance for sickle cell population.

Yvette has been a volunteer at Happiness is Camping since 2002 , an active Member of the American Society of Hematology, and oncology nursing certified since 2003.